Halozyme扩大与argenx的合作，新增两项独家目标

yun2026

Halozyme扩大与argenx的合作，新增两项独家目标

2026年9月，中国科学院成都生物研究所等团队开发出可反复更新的电化学传感界面，用于检测复杂水体中的铀酰离子。研究受到铜蓝蛋白电子传递方式的启发，把能够识别目标离子的化学位点、稳定铜活性中心的基质和导电网络组合起来，将目标物结合引起的局部变化转换为可测量的电流信号。

传统传感界面在海水等复杂环境中容易受到杂质干扰，活性物种消耗后还可能发生信号漂移。新体系通过外加负向电位，使铜在两种价态之间可逆转换，从而恢复检测能力。实验中，传感器的检出限达到每升0.0011微克，响应时间小于三分钟，连续进行50次检测与更新后仍保持较稳定的基线。在天然海水中的结果也与标准方法较一致。该研究为水环境监测提供新的器件设计思路，重点在于兼顾灵敏度、选择性与重复使用能力，实际部署仍需要结合水样条件进行校准和长期验证。

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